A multiplexed screening method for pluripotency
نویسندگان
چکیده
منابع مشابه
A PiggyBac-Based Recessive Screening Method to Identify Pluripotency Regulators
Phenotype driven genetic screens allow unbiased exploration of the genome to discover new biological regulators. Bloom syndrome gene (Blm) deficient embryonic stem (ES) cells provide an opportunity for recessive screening due to frequent loss of heterozygosity. We describe a strategy for isolating regulators of mammalian pluripotency based on conversion to homozygosity of PiggyBac gene trap ins...
متن کاملHigh-throughput mitochondrial genome screening method for nonmelanoma skin cancer using multiplexed temperature gradient capillary electrophoresis.
BACKGROUND We explored the utility of multiplexed temperature gradient capillary electrophoresis (TGCE) as a screening tool for identifying genetic changes in the human mitochondrial genome. We examined changes in mitochondrial DNA (mtDNA) in nonmelanoma skin cancers (NMSCs), using TGCE to resolve genetic differences contained within the tumors compared with the control DNA. METHODS The entir...
متن کاملSelective Tone Reservation Method for PAPR Reduction of Spatially Multiplexed OFDM Systems
Tone Reservation (TR) is one of the well-known methods for PAPR reduction of Orthogonal Frequency Division Multiplexing (OFDM) systems. In this method some sub-carriers are reserved for PAPR reduction and the symbols in these sub-carriers are selected such that the PAPR of the OFDM frame is minimized. In this paper, the iterative algorithm introduced earlier for TR method in single antenna OFDM...
متن کاملMultiplexed Experiment Design in High-Throughput Screening
An early step in the drug discovery involves screening through numerous chemical compounds to find molecules that have a specified biological or biochemical effect. This screening process is costly, thus any modifications to make the screen more efficient would reduce the total cost of drug discovery. Current high-throughput screening methods test each compound from a library of compounds indiv...
متن کاملA New Screening Evaluation Method for Carbon Dioxide Miscible Flooding Candidate Reservoirs
Prior to the implementation of CO2 injection EOR projects, the screening evaluation of candidate reservoirs will promote the economic benefits of CO2 injection. Currently, a uniform screening method for CO2 miscible flooding does not exist. Based on more than 112 successfully implemented CO2 miscible flooding reservoirs, which was referred in 2010 Worldwide EOR Survey, and CO2 miscible flooding...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Stem Cell Research
سال: 2017
ISSN: 1873-5061
DOI: 10.1016/j.scr.2017.07.014